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Rabbit
Anti-MADH7/Smad7/Smad6/Gold
Cat. Number:
bs-0566R-Gold
Quantity size:
100ul
15nm
Concentration:
0.4mg/ml Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
The protein encoded by this gene is a nuclear protein that binds the E3 ubiquitin ligase SMURF2. Upon binding, this complex translocates to the cytoplasm, where it interacts with TGF-beta receptor type-1 (TGFBR1), leading to the degradation of both the encoded protein and TGFBR1. Expression of this gene is induced by TGFBR1. Variations in this gene are a cause of susceptibility to colorectal cancer type 3 (CRCS3). Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2010]
Also known as:
hSMAD 7;
hSMAD7;
MAD (mothers against decapentaplegic Drosophila) homolog 7;
MAD;
Mad homolog 7;
MAD mothers against decapentaplegic homolog 7;
MADH 7;
MADH 8;
MADH8;
Mothers Against Decapentaplegic Drosophila Homolog of 7;
Mothers against decapentaplegic homolog 7;
Mothers against decapentaplegic homolog 8;
Mothers against DPP homolog 7;
Mothers against DPP homolog 8;
SMA- AND MAD-RELATED PROTEIN 7;
SMAD 7;
SMAD;
SMAD family member 7;
SMAD, mothers against DPP homolog 7 (Drosophila);
SMAD, mothers against DPP homolog 7;
Smad7;
SMAD7_HUMAN.
Specificity:
●
Rabbit Polyclonal IgG, affinity purified by Protein A.
●
Reacts with:
(predicted: )
●
Immunogen: KLH conjugated synthetic peptide derived from human Smad7.
●
Predicted Molecular Weight: 46kDa.
Storage:
0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300. Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles.
Application:
Not yet tested in other applications.
Optimal working dilutions must be determined by the end user.
Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.