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Rabbit
Anti-ATG4D/APC
Cat. Number:
bs-4009R-APC
Quantity size:
100ul
Concentration:
1mg/ml Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene belongs to the autophagy-related protein 4 (Atg4) family of C54 endopeptidases. Members of this family encode proteins that play a role in the biogenesis of autophagosomes, which sequester the cytosol and organelles for degradation by lysosomes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
Also known as:
9830134P12Rik;
APG4 autophagy 4 homolog D;
APG4 D;
APG4, S. cerevisiae, homolog of, D;
APG4D;
ATG4 autophagy related 4 homolog D (S. cerevisiae);
Atg4d;
ATG4D_HUMAN;
Atg4dl;
AUT like 4 cysteine endopeptidase;
AUT-like 4 cysteine endopeptidase;
AUTL4;
Autophagin 4;
Autophagin-4;
autophagy 4, S. cerevisiae, homolog of, D;
autophagy related 4D, cysteine peptidase;
Autophagy related cysteine endopeptidase 4;
Autophagy related protein 4 homolog D;
Autophagy-related cysteine endopeptidase 4;
Autophagy-related protein 4 homolog D;
Cysteine protease ATG4D;
Cysteine protease involved in autophagy;
MGC31226.
Specificity:
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Rabbit Polyclonal IgG, affinity purified by Protein A.
●
Reacts with:
(predicted: )
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Immunogen: KLH conjugated synthetic peptide derived from human ATG4D.
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Predicted Molecular Weight: 52kDa.
Storage:
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Application:
Excitation spectrum: 650nm
Emission spectrum: 660nm
Not yet tested in other applications.
Optimal working dilutions must be determined by the end user.
Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.