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Cat. Number:

bs-5447R-AP

Quantity size:

100ul

Concentration:

1mg/ml  Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. [provided by RefSeq, Jul 2008].

Also known as:

IGF1 Receptor (phospho Y980); p-IGF1 Receptor (phospho Y980); IGF1R (phospho-Tyr980); IGF1R (phospho-Y980); p-IGF1R (Tyr980); p-IGF1R (Y980); IGF1R (phospho Tyr980); CD221; CD221; CD221 antigen; IGF 1 receptor; IGF 1R; IGF 1R; IGF I receptor; IGF-I receptor; IGF1R; IGF1R; IGF1R_HUMAN; IGFIR; IGFIRC; IGFIRC; IGFR; Insulin like growth factor 1 receptor; Insulin like growth factor 1 receptor; Insulin like growth factor 1 receptor precursor; Insulin like growth factor 1 receptor precursor; Insulin-like growth factor 1 receptor beta chain; Insulin-like growth factor I receptor; JTK13; JTK13; MGC142170; MGC142172; MGC18216; IGF-IR.

Specificity:

Storage:

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

Application:

Not yet tested in other applications.
Optimal working dilutions must be determined by the end user.

Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.