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Catalog Number:

bs-0789P-PE

Species:

Pig

AA Seq:

Purified native protein

Predicted MW:

5.77754

Activity:

Not tested

Endotoxin:

Not analyzed

Concentration:

>1.0 mg/ml

Storage:

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background:

Insulin from porcine pancreas, 51 amino acids.

Insulin is one of the major regulatory hormones of intermediate metabolism throughout the body. The biological actions of this hormone involve integration of carbohydrate, protein, and lipid metabolism. Insulin enhances membrane transport of glucose, amino acids, and certain ions. It also promotes glycogen storage, formation of triglycerides and synthesis of proteins and nucleic acids. Immunocytochemical investigations have localized insulin in the B cells of pancreatic islets of Langerhans. Deficiency of insulin results in diabetes mellitus, one of the leading causes of morbidity and mortality in the general population. Insulin is also present in tumors of B cell origin such as insulinoma.