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产品编号:

bsk11006

产品规格:

96T    

保存条件:

Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Shipped with wet ice.)

别名:

IL 23; IL 23A; IL23P19; Interleukin 23 alpha subunit p19; JKA3 induced upon T cell activation; P19; SGRF; IL-23 subunit alpha; IL-23-A; IL-23p19; IL23; Il23a; IL23A_HUMAN; Interleukin 23 p19 subunit; Interleukin-23 subunit alpha; Interleukin-23 subunit p19; JKA3 induced upon T cell activation; MGC79388; P19.

种属:

Human

线性范围:

31.25 - 2,000 pg/mL

应用范围:

S/P/CC

检测限:

16 pg/mL

产品介绍:

IL23 is a heterodimeric cytokine consisting in two subunits : p40, shared with IL12 and a distinct one p19 (the IL23 subunit). Although IL12 activates naive T cells, the initial description of IL23 was the preferential action on memory T cells to increase IFNg production. In conjunction with IL6 and TGF-beta1, IL23 is necessary to maintain the Th1 lineage. IL23 plays an important role in the inflammatory response against infection, and is implicated in the development of cancerous tumors and auto immune diseases. Over expression of p19 correlates with inflammation in multiple organs and epithelial tissues including skin.