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Rabbit
Anti-B7-DC/FITC
Cat. Number:
bs-1868R-FITC
Quantity size:
100ul
Concentration:
1mg/ml Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
B7DC is a 33kDa member of the immunoglobulin receptor superfamily expressed on DC, liver and a small subset of macrophages as well as a few transformed cell lines. B7DC has been reported to be stimulatory on dendritic cells when cross linked and to inhibit T cell activation upon engaging the PD1 receptor. B7DC has also been reported to bind to an alternative receptor and to mediate T cell activation through non PD1 mediated interactions.
Also known as:
PD L2;
B7 dendritic cell molecule;
B7-DC;
B7DC;
bA574F11.2;
Btdc;
Butyrophilin B7 DC;
Butyrophilin B7-DC;
Butyrophilin B7DC;
CD 273;
CD273;
CD273 antigen;
MGC142238;
MGC142240;
PD 1 ligand 2;
PD-1 ligand 2;
PD-L2;
PD1 ligand 2;
PD1L2_HUMAN;
PDCD 1 ligand 2;
PDCD1 ligand 2;
PDCD1L2;
Pdcd1lg2;
PDL 2;
PDL2;
Programmed cell death 1 ligand 2;
Programmed death ligand 2.
Specificity:
●
Rabbit Polyclonal IgG, affinity purified by Protein A.
●
Reacts with:
(predicted: )
●
Immunogen: KLH conjugated synthetic peptide derived from human B7-DC.
●
Predicted Molecular Weight: 29kDa.
Storage:
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Application:
Excitation spectrum: 495nm
Emission spectrum: 519nm
Not yet tested in other applications.
Optimal working dilutions must be determined by the end user.
Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.