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Cat. Number:

bs-18933R-AF594

Quantity size:

100ul

Concentration:

1mg/ml  Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

MICAL2 is a 1,124 amino acid protein that localizes to both the cytoplasm and the cytoskeleton and contains one LIM zinc-binding domain and one calponin-homology domain. Using FAD as a cofactor, MICAL2 interacts with Rab 1B, plexin-A4 and Vimentin and, via these interactions, may play a role in cytoskeletal regulation, specifically at intermediate filaments. MICAL2, which exists as two alternatively spliced isoforms, is expressed at high levels in heart and brain and at lower levels in ovary, skeletal muscle, liver, testis and kidney tissue.

Also known as:

flavoprotein oxidoreductase MICAL2; KIAA0750; MICAL2PV1; MICAL2PV2; microtubule associated monoxygenase, calponin and LIM domain containing 2; Molecule interacting with CasL protein 2; Protein-methionine sulfoxide oxidase MICAL2.

Specificity:

Storage:

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

Application:

Not yet tested in other applications.
Optimal working dilutions must be determined by the end user.

Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.