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Rabbit
Anti-VPS24/PE
Cat. Number:
bs-12767R-PE
Concentration:
1mg/ml Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
This gene encodes a protein that sorts transmembrane proteins into lysosomes/vacuoles via the multivesicular body (MVB) pathway. This protein, along with other soluble coiled-coil containing proteins, forms part of the ESCRT-III protein complex that binds to the endosomal membrane and recruits additional cofactors for protein sorting into the MVB. This protein may also co-immunoprecipitate with a member of the IFG-binding protein superfamily. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the upstream ring finger protein 103 (RNF103) gene. [provided by RefSeq, Nov 2010]
Also known as:
VPS 24;
VPS24;
CGI 149;
CGI149 protein;
Charged multivesicular body protein 3;
CHMP3;
CHMP3_HUMAN;
Chromatin modifying protein 3;
Chromatin-modifying protein 3;
HGNC:29865;
hVps24;
NEDF;
Neuroendocrine differentiation factor;
Vacuolar protein sorting 24 (yeast);
Vacuolar protein sorting 24 homolog (S. cerevisiae);
Vacuolar protein sorting associated protein 24;
Vacuolar protein sorting-associated protein 24;
VPS 24;
VPS24.
Specificity:
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Rabbit Polyclonal IgG, affinity purified by Protein A.
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Reacts with:
(predicted: )
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Immunogen: KLH conjugated synthetic peptide derived from human VPS24.
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Predicted Molecular Weight: 25kDa.
Storage:
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Application:
Excitation spectrum: 496nm,564nm
Emission spectrum: 578nm
Not yet tested in other applications.
Optimal working dilutions must be determined by the end user.
Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.