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Rabbit  Anti-NAS6/AP
Cat. Number:
bs-19025R-AP
Quantity size:
100ul
Concentration:
1mg/ml  Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
NAS6 (p28) is a proteasome-interacting protein which acts as a chaperone to assemble the base sub-complex of the 19S RP which is involved in the ATP-dependent degradation of ubiquitinated proteins. NAS6 is composed of 226 amino acid residues with calculated molecular masses of 24.4kD.
Also known as:
Nas6p; ortholog of human oncoprotein gankyrin, which interacts with the Rb tumor suppressor and CDK4/6; Probable 26S proteasome regulatory subunit p28; Proteasome interacting protein involved in the assembly of the base subcomplex of the 19S proteasomal regulatory particle (RP); Proteasome non ATPase subunit 6.
Specificity:
Rabbit Polyclonal IgG, affinity purified by Protein A.
Reacts with: (predicted: )
Immunogen: KLH conjugated synthetic peptide derived from human NAS6.
Predicted Molecular Weight: 26kDa.
Storage:
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Application:

Not yet tested in other applications.
Optimal working dilutions must be determined by the end user.
Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.