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Rabbit
Anti-TNNI3/FITC
Cat. Number:
bs-10613R-FITC
Concentration:
1mg/ml Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit; blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. This gene encodes the TnI-cardiac protein and is exclusively expressed in cardiac muscle tissues. Mutations in this gene cause familial hypertrophic cardiomyopathy type 7 (CMH7) and familial restrictive cardiomyopathy (RCM). [provided by RefSeq].
Also known as:
Cardiac Troponin I; cardiac muscle; Troponin I, cardiac muscle;
Cardiomyopathy, familial hypertrophic, 7, included;
CMD1FF;
CMD2A;
CMH7;
cTnI;
Familial hypertrophic cardiomyopathy 7;
MGC116817;
RCM1;
Tn1;
Tni;
TNN I3;
TNNC 1;
TNNC1;
TNNI3;
TNNI3;
TNNI3_HUMAN;
Troponin I;
Troponin I cardiac;
Troponin I cardiac muscle;
Troponin I cardiac muscle isoform;
Troponin I type 3 cardiac;
troponin I, cardiac 3;
TroponinI;
Ttroponin I type 3 (cardiac).
Specificity:
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Rabbit Polyclonal IgG, affinity purified by Protein A.
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Reacts with:
(predicted: )
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Immunogen: KLH conjugated synthetic peptide derived from human TNNI3.
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Predicted Molecular Weight: 24kDa.
Storage:
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Application:
Excitation spectrum: 495nm
Emission spectrum: 519nm
Not yet tested in other applications.
Optimal working dilutions must be determined by the end user.
Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.