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Rabbit
Anti-SH3KBP1/AF488
Cat. Number:
bs-16723R-AF488
Quantity size:
100ul
Concentration:
1mg/ml Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
SHKBP1 is a 707 amino acid protein belonging to the KCTD3 family. Acting downstream of Flt-3/Flk-2, SHKBP1 interacts with CIN85. SHKBP1 contains a BTB/POZ domain, which is involved in ring canal formation and chromatin folding, and five WB repeats. SHKBP1 exists as two alternatively spliced isoforms and maps to human chromosome 19q13.2. Chromosome 19 consists of over 63 million bases, houses approximately 1,400 genes and is recognized for having the greatest gene density of the human chromosomes. It is the genetic home for a number of immunoglobulin (Ig) superfamily members, including the killer cell and leukocyte Ig-like receptors, a number of ICAMs, the CEACAM and PSG families and Fc receptors (FcRs).
Also known as:
c Cbl interacting protein;
Cbl interacting protein;
Cbl interacting protein of 85 kDa;
Cbl-interacting protein of 85 kDa;
CD2 binding protein 3;
CD2-binding protein 3;
CD2BP3;
CIN 85;
CIN85;
GIG 10;
GIG10;
HSB 1;
HSB-1;
HSB1;
Human Src family kinase binding protein 1;
Human Src family kinase-binding protein 1;
MIG 18;
MIG18;
Migration inducing gene 18;
Migration inducing gene 18 protein;
SH3 domain kinase binding protein 1;
SH3 domain-containing kinase-binding protein 1;
SH3BP 1;
SH3K1_HUMAN;
SH3KBP1;
Src family kinase binding protein 1;
src related kinase binding protein 1.
Specificity:
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Rabbit Polyclonal IgG, affinity purified by Protein A.
●
Reacts with:
(predicted: )
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Immunogen: KLH conjugated synthetic peptide derived from human SH3KBP1.
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Predicted Molecular Weight: 73kDa.
Storage:
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Application:
Excitation spectrum: 495nm
Emission spectrum: 519nm
Not yet tested in other applications.
Optimal working dilutions must be determined by the end user.
Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.