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Rabbit Anti-GAL3ST1/RBITC Conjugated antibody (bs-16213R-RBITC)
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说 明 书: 100ul  
100ul/2980.00元
大包装/询价
产品编号 bs-16213R-RBITC
英文名称1 Rabbit Anti-GAL3ST1/RBITC Conjugated antibody
中文名称 罗丹明(RBITC)标记的半乳糖神经酰胺磺基转移酶抗体
别    名 3' phosphoadenosine 5' phosphosulfate:GalCer sulfotransferase; 3' phosphoadenylylsulfate:galactosylceramide 3' sulfotransferase; 3''-phosphoadenosine-5''-phosphosulfate:GalCer sulfotransferase; 3''-phosphoadenylylsulfate:galactosylceramide 3''-sulfotransferase; Cerebroside (3' phosphoadenylylsulfate:galactosylceramide 3') sulfotransferase; Cerebroside sulfotransferase; CST; G3ST1_HUMAN; GAL3ST1; Galactose 3 O sulfotransferase 1; Galactosylceramide sulfotransferase; GalCer sulfotransferase.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 肿瘤  细胞生物  神经生物学  信号转导  新陈代谢  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep, )
产品应用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 49kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human GAL3ST1
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
Sulfonation, an important step in the metabolism of many drugs, xenobiotics, hormones, and neurotransmitters, is catalyzed by sulfotransferases. The product of this gene is galactosylceramide sulfotransferase which catalyzes the conversion between 3'-phosphoadenylylsulfate + a galactosylceramide to adenosine 3',5'-bisphosphate + galactosylceramide sulfate. Activity of this sulfotransferase is enhanced in renal cell carcinoma. [provided by RefSeq, Jul 2008]

Function:
Catalyzes the sulfation of membrane glycolipids. Seems to prefer beta-glycosides at the non-reducing termini of sugar chains attached to a lipid moiety. Catalyzes the synthesis of galactosylceramide sulfate (sulfatide), a major lipid component of the myelin sheath and of monogalactosylalkylacylglycerol sulfate (seminolipid), present in spermatocytes (By similarity). Also acts on lactosylceramide, galactosyl 1-alkyl-2-sn-glycerol and galactosyl diacylglycerol (in vitro).

Subcellular Location:
Golgi apparatus membrane.

Tissue Specificity:
Expressed in kidney proximal tubule, gastric mucosa and adenocarcinoma. Highly expressed in renal cell carcinoma cell lines.

Similarity:
Belongs to the galactose-3-O-sulfotransferase family.

Database links:

Entrez Gene: 9514 Human

Omim: 602300 Human

SwissProt: Q99999 Human

Unigene: 17958 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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