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Rabbit Anti-ENTPD4/BF647 Conjugated antibody (bs-14601R-BF647)
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说 明 书: 100ul  
100ul/2980.00元
大包装/询价
产品编号 bs-14601R-BF647
英文名称1 Rabbit Anti-ENTPD4/BF647 Conjugated antibody
中文名称 BF647标记的ENTPD4蛋白抗体
别    名 Apyrase lysosomal; Ectonucleoside triphosphate diphosphohydrolase 4; ENTPD 4; Golgi luminal UDPase; Guanosine diphosphatase like protein; KIAA0392; LALP70; ENTP4_HUMAN; LAP70; LYSAL1; Lysosomal apyrase like 1; Lysosomal apyrase like protein of 70 kDa; NTPDase 4; UDPase; Uridine diphosphatase  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 肿瘤  细胞生物  信号转导  新陈代谢  表观遗传学  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, )
产品应用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 70kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human ENTPD4
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
This gene encodes a member of the apyrase protein family. Apyrases are enzymes that catalyze the hydrolysis of nucleotide diphosphates and triphosphates in a calcium or magnesium-dependent manner. The encoded protein is an endo-apyrase and may play a role in salvaging nucleotides from lysosomes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and these isoforms may differ in divalent cation dependence and substrate specificity. [provided by RefSeq, Sep 2011]

Function:
ENTPD4 (Ectonucleoside triphosphate diphosphohydrolase 4) preferentially hydrolyzes nucleoside 5'-diphosphates. Nucleoside 5'-triphosphates are hydrolyzed only to a minor extent. The order of activity with different substrates is UDP >> GDP = CDP = TDP. AMP, ADP, ATP and UMP are not substrates. There are two named isoforms. The preferred substrates for isoform 2 are CTP, UDP, CDP, GTP and GDP, while isoform 1 utilizes UTP and TTP.

Subcellular Location:
Golgi apparatus membrane; Multi-pass membrane protein. Cytoplasmic vesicle, autophagosome membrane; Multi-pass membrane protein. Note: Localizes in the Golgi and autophagic vacuoles/lysosomes.

Tissue Specificity:
Ubiquitous. Highest expression in testis and lowest in bladder.

Similarity:
Belongs to the GDA1/CD39 NTPase family.

Database links:

Entrez Gene: 9583 Human

Entrez Gene: 67464 Mouse

Entrez Gene: 361063 Rat

Omim: 607577 Human

SwissProt: Q9Y227 Human

SwissProt: Q9DBT4 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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