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Rabbit Anti-SLC14A2/RBITC Conjugated antibody (bs-11801R-RBITC) ~~~促销,代码KX240301~~~
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说 明 书: 100ul  
100ul/2980.00元
大包装/询价
产品编号 bs-11801R-RBITC
英文名称 Anti-SLC14A2/RBITC
中文名称 罗丹明(RBITC)标记的尿素转运型糖蛋白A2抗体
别    名 UT-A; HUT2; kidney; MGC119566; MGC119567; Slc14a2; Solute carrier family 14 (urea transporter), member 2; Solute carrier family 14 member 2; Urea transporter 2; Urea transporter; Urea transporter, kidney; UT-A2; UT2; UT2_HUMAN; UTA; UTR; FLJ16167; hUT-A6.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 肿瘤  神经生物学  信号转导  通道蛋白  新陈代谢  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 (predicted: Human, Mouse, Rat, )
产品应用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 101kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human SLC14A2/UT-A
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
The protein encoded by this gene belongs to the urea transporter family. In mammalian cells, urea is the chief end product of nitrogen catabolism, and plays an important role in the urinary concentration mechanism. This protein is expressed in the inner medulla of the kidney, and mediates rapid transepithelial urea transport across the inner medullary collecting duct. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2011]

Function:
Specialized low-affinity vasopressin-regulated urea transporter. Mediates rapid transepithelial urea transport across the inner medullary collecting duct and plays a major role in the urinary concentrating mechanism.

Subunit:
Isoform 1 interacts with SNAPIN which may be important for recruitment to the plasma membrane.

Subcellular Location:
Apical cell membrane; Multi-pass membrane protein.

Tissue Specificity:
Isoform 1 and isoform 2 are expressed in the inner medulla of the kidney.

Similarity:
Belongs to the urea transporter family.

Database links:

Entrez Gene: 8170 Human

Entrez Gene: 27411 Mouse

Entrez Gene: 54302 Rat

Omim: 601611 Human

SwissProt: Q15849 Human

SwissProt: Q8R4T9 Mouse

SwissProt: Q62668 Rat

Unigene: 710927 Human

Unigene: 44158 Mouse

Unigene: 10157 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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