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Rabbit Anti-Reticulon 1/Gold Conjugated antibody (bs-11798R-Gold) ~~~促销,代码KX240301~~~
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说 明 书: 100ul(10nm  15nm  35nm
100ul/2980.00元
大包装/询价
产品编号 bs-11798R-Gold
英文名称 Anti-Reticulon 1/Gold
中文名称 胶体金标记的神经内分泌特异性蛋白抗体
别    名 MGC133250; Neuroendocrine specific protein; NSP; Reticulon 1; Reticulon1; Reticulon1A; RTN 1; RTN1; RTN1 protein; RTN1_HUMAN.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul(10nm  15nm  35nm
研究领域 肿瘤  细胞生物  神经生物学  肿瘤细胞生物标志物  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 (predicted: Human, Mouse, Rat, Pig, )
产品应用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 84kDa
性    状 Lyophilized or Liquid
浓    度 0.4mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Reticulon 1
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
保存条件 Store at 2-8 ºC for 3-6 months. Avoid repeated freeze/thaw cycles.
产品介绍 background:
This gene belongs to the family of reticulon encoding genes. Reticulons are associated with the endoplasmic reticulum, and are involved in neuroendocrine secretion or in membrane trafficking in neuroendocrine cells. This gene is considered to be a specific marker for neurological diseases and cancer, and is a potential molecular target for therapy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2011]

Function:
May be involved in neuroendocrine secretion or in membrane trafficking in neuroendocrine cells.

Subunit:
Interacts with NDRG1.

Subcellular Location:
Endoplasmic reticulum membrane; Multi-pass membrane protein.

Tissue Specificity:
Expressed in neural and neuroendocrine tissues and cell cultures derived therefrom. Expression of isoform RTN1-C is strongly correlated with neuronal differentiation.

Post-translational modifications:
Isoforms RTN1-A and RTN1-B are phosphorylated.

Similarity:
Contains 1 reticulon domain.

Database links:

Entrez Gene: 6252 Human

Entrez Gene: 116644 Rat

Omim: 600865 Human

SwissProt: Q16799 Human

SwissProt: Q64548 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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