产品编号 | bs-16213R |
英文名称 | Rabbit Anti-GAL3ST1 antibody |
中文名称 | 半乳糖神经酰胺磺基转移酶抗体 |
别 名 | 3' phosphoadenosine 5' phosphosulfate:GalCer sulfotransferase; 3' phosphoadenylylsulfate:galactosylceramide 3' sulfotransferase; 3''-phosphoadenosine-5''-phosphosulfate:GalCer sulfotransferase; 3''-phosphoadenylylsulfate:galactosylceramide 3''-sulfotransferase; Cerebroside (3' phosphoadenylylsulfate:galactosylceramide 3') sulfotransferase; Cerebroside sulfotransferase; CST; G3ST1_HUMAN; GAL3ST1; Galactose 3 O sulfotransferase 1; Galactosylceramide sulfotransferase; GalCer sulfotransferase. |
研究领域 | 肿瘤 细胞生物 神经生物学 信号转导 新陈代谢 |
抗体来源 | Rabbit |
克隆类型 | Polyclonal |
交叉反应 | (predicted: Human,Mouse,Rat,Pig,Sheep,Cow,Dog,Horse) |
产品应用 | IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理论分子量 | 49kDa |
细胞定位 | 细胞浆 |
性 状 | Liquid |
浓 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human GAL3ST1: 331-423/423 |
亚 型 | IgG |
纯化方法 | affinity purified by Protein A |
缓 冲 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
产品介绍 |
Sulfonation, an important step in the metabolism of many drugs, xenobiotics, hormones, and neurotransmitters, is catalyzed by sulfotransferases. The product of this gene is galactosylceramide sulfotransferase which catalyzes the conversion between 3'-phosphoadenylylsulfate + a galactosylceramide to adenosine 3',5'-bisphosphate + galactosylceramide sulfate. Activity of this sulfotransferase is enhanced in renal cell carcinoma. [provided by RefSeq, Jul 2008] Function: Catalyzes the sulfation of membrane glycolipids. Seems to prefer beta-glycosides at the non-reducing termini of sugar chains attached to a lipid moiety. Catalyzes the synthesis of galactosylceramide sulfate (sulfatide), a major lipid component of the myelin sheath and of monogalactosylalkylacylglycerol sulfate (seminolipid), present in spermatocytes (By similarity). Also acts on lactosylceramide, galactosyl 1-alkyl-2-sn-glycerol and galactosyl diacylglycerol (in vitro). Subcellular Location: Golgi apparatus membrane. Tissue Specificity: Expressed in kidney proximal tubule, gastric mucosa and adenocarcinoma. Highly expressed in renal cell carcinoma cell lines. Similarity: Belongs to the galactose-3-O-sulfotransferase family. SWISS: Q99999 Gene ID: 9514 Database links: Entrez Gene: 9514 Human Omim: 602300 Human SwissProt: Q99999 Human Unigene: 17958 Human |
1、抗体溶解方法 | |
2、抗体修复方式 | |
3、常用试剂的配制 | |
4、免疫组化操作步骤 | |
5、免疫组化问题解答 | |
6、Western Blotting 操作步骤 | |
7、Western Blotting 问题解答 | |
8、关于肽链的设计 | |
9、多肽的溶解与保存 | |
10、酶标抗体效价测定程序 | |