产品编号 | bs-2691R |
英文名称 | LILRB3/CD85a |
中文名称 | 白细胞免疫球蛋白样受体-B抗体 |
别 名 | CD85 antigen like family member A; CD85a; CD85a antigen; HL9; IL T5; ILT5; Immunoglobulin like transcript 5; Leukocyte immunoglobulin like receptor 3; Leukocyte immunoglobulin like receptor subfamily B (with TM and ITIM domains) member 3; Leukocyte immunoglobulin like receptor subfamily B member 3; LIR 3; LIR3; Gp91; Pirb; MGC138403; Monocyte inhibitory receptor HL9; PIRB; Lilrb3; 16M4; 16M5; 16M6; 6M1; 7M5; PIRB1; PIRB2; PIRB3; PIRB4;PIRB5. |
研究领域 | 免疫学 |
抗体来源 | Rabbit |
克隆类型 | Polyclonal |
交叉反应 | Human |
产品应用 | WB=1:500-2000, IHC-P=1:100-500, IHC-F=1:100-500, ICC=1:100-500, IF=1:100-500, Flow-Cyt=1μg /test, ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理论分子量 | 67kDa |
细胞定位 | 细胞膜 |
性 状 | Liquid |
浓 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human LILRB3: 51-150/631 <Extracellular> |
亚 型 | IgG |
纯化方法 | affinity purified by Protein A |
缓 冲 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存条件 | Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
产品介绍 |
This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] Function: May act as receptor for class I MHC antigens. Subcellular Location: Membrane; Single-pass type I membrane protein. Tissue Specificity: Detected in monocytes and B-cells. SWISS: O75022 Gene ID: 11025 Database links: Entrez Gene: 11025 Human Omim: 604820 Human SwissProt: O75022 Human Unigene: 631592 Human |
产品图片 |
Blank control(blue):Raji(fixed with 2% paraformaldehyde (10 min)).
Primary Antibody:Rabbit Anti-CD85a antibody(bs-2691R), Dilution: 1μg in 100 μL 1X PBS containing 0.5% BSA; Isotype Control Antibody: Rabbit IgG(orange) ,used under the same conditions ); Secondary Antibody: Goat anti-rabbit IgG-PE(white blue), Dilution: 1:200 in 1 X PBS containing 0.5% BSA. |
1、抗体溶解方法 | |
2、抗体修复方式 | |
3、常用试剂的配制 | |
4、免疫组化操作步骤 | |
5、免疫组化问题解答 | |
6、Western Blotting 操作步骤 | |
7、Western Blotting 问题解答 | |
8、关于肽链的设计 | |
9、多肽的溶解与保存 | |
10、酶标抗体效价测定程序 | |