Host: Rabbit

Target Protein: CD66c

IR: Immunogen Range:165-260/344

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 4680

Swiss Prot: P40199

Source: KLH conjugated synthetic peptide derived from human CD66c/CEACAM6:165-260/344 

Purification: affinity purified by Protein A

Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background: The CD66c immunoglobulin superfamily of genes encode cell adhesion proteins, which are expressed at higher levels in tumorous tissues than in normal tissues. CD66 mRNA is strongly expressed in primary colon tumors and, to a lesser extent, in normal colonic tissue. The human CD66 gene family is a diverse set of glycoproteins of epithelial and hematopoietic lineage that comprises 29 genes, which map to chromosome position 19q13.1-q13.2. CD66A, CD66B, CD66C, CD66D, CD66E and CD66F are the best characterized CD66 antigens, and CD66A-D expression upregulates on the surface of granulocytes upon stimulation. Certain CD66 isoforms mediate homotypic and heterotypic intercellular adhesion events independently of cell type.