Host: Rabbit
Target Protein: NHERF1
IR: Immunogen Range:281-358/358
Clonality: Polyclonal
Isotype: IgG
Entrez Gene: 9368
Swiss Prot: O14745
Source: KLH conjugated synthetic peptide derived from human EBP50/SLC9A3R1:281-358/358
Purification: affinity purified by Protein A
Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background: Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression. Necessary for recycling of internalized ADRB2. Was first known to play a role in the regulation of the activity and subcellular location of SLC9A3. Necessary for cAMP-mediated phosphorylation and inhibition of SLC9A3. May enhance Wnt signaling. May participate in HTR4 targeting to microvilli (By similarity). Interacts with MCC.
Size: 200ul
Concentration: 1mg/ml
Applications: WB=1:500-2000, ELISA=1:5000-10000
Cross Reactive Species: (predicted: Human,Mouse,Rat,Chicken,Pig,Cow,Rabbit)
For research use only. Not intended for diagnostic or therapeutic use.