Host: Rabbit
Target Protein: Phospho-RhoA (Ser188)
IR: Immunogen Range:KK(p-S)GC
Clonality: Polyclonal
Isotype: IgG
Entrez Gene: 387
Swiss Prot: P61586
Source: KLH conjugated Synthesised phosphopeptide derived from human RhoA around the phosphorylation site of Ser188:KK(p-S)GC
Purification: affinity purified by Protein A
Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background: This gene encodes a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility. The protein encoded by this gene is prenylated at its C-terminus, and localizes to the cytoplasm and plasma membrane. It is thought to be important in cell locomotion. Overexpression of this gene is associated with tumor cell proliferation and metastasis. Multiple alternatively spliced variants, encoding the same protein, have been identified.
Size: 200ul
Concentration: 1mg/ml
Applications: WB=1:500-2000, IHC-P=1:100-500, IHC-F=1:100-500, IF=1:100-500, Flow-Cyt=1μg/Test, ELISA=1:5000-10000
Cross Reactive Species: Human,Rat (predicted: Mouse,Chicken,Dog,Cow,Sheep)
For research use only. Not intended for diagnostic or therapeutic use.