Host: Rabbit

Target Protein: ZnT-1 Rabbit pAb

IR: Immunogen Range:131-330/507

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 7779

Swiss Prot: Q9Y6M5

Source: KLH conjugated synthetic peptide derived from human ZnT-1:131-330/507 

Purification: affinity purified by Protein A

Storage: 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.

Background: Zinc, an essential element required for cell proliferation and differentiation, plays a role in a diverse array of cellular functions, including acting as a cofactor for numerous enzymes and transcription factors and as a neuroregulator. The zinc transporter (ZnT) family regulates the supply of zinc within cells, and its members are characterized by containing six membrane-spanning domains, a large histidine-rich intracellular loop, and a C-terminal tail. ZnT-1, a ubiquitous protein, localizes to the plasma membrane to aid in the export of zinc out of cells.