Host: Rabbit
Target Protein: KDEL
IR: Immunogen Range:
Clonality: Polyclonal
Isotype: IgG
Entrez Gene: 79070
Swiss Prot: Q6UW63
Source: KLH conjugated synthetic peptide KDEL:
Purification: affinity purified by Protein A
Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:
Endoplasmic reticulum Marker.
The sequence Lys-Asp-Glu-Leu (KDEL) or a closely related sequence, is present at the carboxy-terminus of soluble endoplasmic reticulum (ER) resident proteins and some membrane proteins. 78 and 94 kDa glucose regulated proteins (GRP 78) and GRP 94 respectively and protein disulfide isomerase (PDI) all share the C-terminal KDEL sequence. The presence of carboxy-terminal KDEL appears to be necessary for ER retention and appears to be sufficient to reduce the secretion of proteins from the ER. This retention is reported to be mediated by a KDEL receptor.
Size: 50ul
Concentration: 1mg/ml
Applications: IHC-P=1:100-500, IHC-F=1:100-500, IF=1:100-500, Flow-Cyt=2ug/test, ELISA=1:5000-10000
Cross Reactive Species: Mouse,Rat (predicted: Human,Dog,Pig,Cow,Rabbit,GuineaPig)
For research use only. Not intended for diagnostic or therapeutic use.