Host: Rabbit

Target Protein: CDCA2

IR: Immunogen Range:361-450/1023

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 157313

Swiss Prot: Q69YH5

Source: KLH conjugated synthetic peptide derived from human CDCA2:361-450/1023 

Purification: affinity purified by Protein A

Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background: CDCA2 is a regulator of chromosome structure during mitosis. CDCA2 forms an essential complex with protein phosphatase PP1-gamma subunit 1 (PPP1CC) and is required for the recruitment of PP1 to chromatin. Knockdown of CDCA2 by RNAi causes large-scale cell death by apoptosis, as does overexpression of a dominant-negative mutant of the protein.