Host: Rabbit

Target Protein: TReP132

IR: Immunogen Range:101-200/1200

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 55809

Swiss Prot: Q96PN7

Source: KLH conjugated synthetic peptide derived from human TReP132/RAPA:101-200/1200 

Purification: affinity purified by Protein A

Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background: Activates transcription of CYP11A1. Interaction with CREBBP and EP300 results in a synergistic transcriptional activation of CYP11A1. Tissue specificity:Highest expression was seen in thymus, testis and adrenal cortex, expressed also in the adrenal medulla, thyroid, and stomach. Highly expressed in steroidogenic JEG-3 and MCF-7 cells, low expression was seen in non-steroidogenic HepG2 and HK293 cells.