Host: Rabbit
Target Protein: DOCK1
IR: Immunogen Range:465-550/1865
Clonality: Polyclonal
Isotype: IgG
Entrez Gene: 1793
Swiss Prot: Q14185
Source: KLH conjugated synthetic peptide derived from human DOCK1:465-550/1865
Purification: affinity purified by Protein A
Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:
Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Functions as a guanine nucleotide exchange factor (GEF), which activates Rac Rho small GTPases by exchanging bound GDP for free GTP. Its GEF activity may be enhanced by ELMO1.
Tissue specificity: Highly expressed in placenta, lung, kidney, pancreas and ovary. Expressed at intermediate level in thymus, testes and colon.
Size: 200ul
Concentration: 1mg/ml
Applications: IHC-P=1:100-500, IHC-F=1:100-500, IF=1:100-500, ELISA=1:5000-10000
Cross Reactive Species: Mouse (predicted: Human,Rat,Chicken,Dog,Cow,Horse,Sheep)
For research use only. Not intended for diagnostic or therapeutic use.