Host: Rabbit

Target Protein: TNFAIP3 interacting protein 3

IR: Immunogen Range:51-150/325

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 79931

Swiss Prot: Q96KP6

Source: KLH conjugated synthetic peptide derived from human TNFAIP3 interacting protein 3/ABIN3:51-150/325 

Purification: affinity purified by Protein A

Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background: ABIN-3 is a member of the A20-binding inhibitor of NF-kappaB activation (ABIN) protein family. Similar to the previously characterized human ABINs (ABIN-1 and ABIN-2), ABIN-3 can bind to A20 and inhibit NF-kappaB activation. In contrast, mouse ABIN-3 is incapable of inhibiting NF-kappaB activation by proinflammatory stimuli because the protein lacks a complete ABIN homology domain, which is required for the funcitonal activity of human ABIN-3.