Host: Rabbit
Target Protein: PGC1 beta
IR: Immunogen Range:901-1023/1023
Clonality: Polyclonal
Isotype: IgG
Entrez Gene: 133522
Swiss Prot: Q86YN6
Source: KLH conjugated synthetic peptide derived from human PGC1 beta:901-1023/1023
Purification: affinity purified by Protein A
Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:
Plays a role of stimulator of transcription factors and nuclear receptors activities. Activates transcritional activity of estrogen receptor alpha, nuclear respiratory factor 1 (NRF1) and glucocorticoid receptor in the presence of glucocorticoids. May play a role in constitutive non-adrenergic-mediated mitochondrial biogenesis as suggested by increased basal oxygen consumption and mitochondrial number when overexpressed. May be involved in fat oxidation and non-oxidative glucose metabolism and in the regulation of energy expenditure.
Tissue specificity:
Ubiquitous with higher expression in heart, brain and skeletal muscle.
Size: 200ul
Concentration: 1mg/ml
Applications: WB=1:500-2000, IHC-P=1:100-500, IHC-F=1:100-500, IF=1:100-500, ELISA=1:5000-10000
Cross Reactive Species: (predicted: Human,Mouse,Rat,Dog,Pig,Cow,Rabbit,GuineaPig)
For research use only. Not intended for diagnostic or therapeutic use.