Host: Rabbit

Target Protein: Myosin light chain (phospho S20)

IR: Immunogen Range:AT(p-S)NV

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 10398

Swiss Prot: P24844

Source: KLH conjugated synthesised phosphopeptide derived from human MYL9 around the phosphorylation site of Ser20:AT(p-S)NV 

Purification: affinity purified by Protein A

Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background: Myosin light chain (MLC) is a subunit of the conventional myosins (e.g. myosin II). In smooth muscle and non-muscle cells conventional myosins mediate a wide variety of contractile events including cytokinesis, cell motility, and smooth muscle contraction. MLC is phosphorylated by multiple serine-threonine kinases such as Rho-kinase and PAK, however myosin light chain kinase (MLCK) acts as the primary kinase. Contractile activity of conventional myosins is regulated by phosphorylation of MLC on several residues.