Host: Rabbit
Target Protein: GAD65
IR: Immunogen Range:501-585/585
Clonality: Polyclonal
Isotype: IgG
Entrez Gene: 2572
Swiss Prot: Q05329
Source: KLH conjugated synthetic peptide derived from human GAD65:501-585/585
Purification: affinity purified by Protein A
Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background: This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantibody and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Alternative splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Oct 2008]
Size: 50ul
Concentration: 1mg/ml
Applications: WB=1:500-2000, ELISA=1:5000-10000
Cross Reactive Species: Human,Mouse,Rat
For research use only. Not intended for diagnostic or therapeutic use.