Host: Rabbit

Target Protein: ATG4C

IR: Immunogen Range:201-300/458

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 84938

Swiss Prot: Q96DT6

Source: KLH conjugated synthetic peptide derived from human ATG4C:201-300/458 

Purification: affinity purified by Protein A

Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background: Cysteine protease required for autophagy, which cleaves the C-terminal part of either MAP1LC3, GABARAPL2 or GABARAP, allowing the liberation of form I. A subpopulation of form I is subsequently converted to a smaller form (form II). Form II, with a revealed C-terminal glycine, is considered to be the phosphatidylethanolamine (PE)-conjugated form, and has the capacity for the binding to autophagosomes.