Host: Rabbit
Target Protein: DIO2
IR: Immunogen Range:101-200/273
Clonality: Polyclonal
Isotype: IgG
Entrez Gene: 1734
Swiss Prot: Q92813
Source: KLH conjugated synthetic peptide derived from human DIO2:101-200/273
Purification: affinity purified by Protein A
Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background: DIO2 belongs to the iodothyronine deiodinase family and is responsible for the deiodination of T4 (3,5,3',5'-tetraiodothyronine) into T3 (3,5,3'-triiodothyronine). It is essential for providing the brain with appropriate levels of T3 during the critical period of development. DIO2 is expressed in heart, skeletal muscle, placenta, fetal brain and several regions of the adult brain. There are two named isoforms.
Size: 50ul
Concentration: 1mg/ml
Applications: WB=1:500-2000, IHC-P=1:100-500, IHC-F=1:100-500, IF=1:100-500, ELISA=1:5000-10000
Cross Reactive Species: Rat,Mouse,Human (predicted: Sheep,Rabbit,Horse,Cow,Pig,Dog)
For research use only. Not intended for diagnostic or therapeutic use.