Host: Rabbit

Target Protein: Phospho-eNOS (Ser1177) Rabbit pAb

IR: Immunogen Range:TQ(p-S)FS

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 18127

Swiss Prot: P70313

Source: KLH conjugated Synthesised phosphopeptide derived from mouse eNOS around the phosphorylation site of Ser1177:TQ(p-S)FS 

Purification: affinity purified by Protein A

Storage: 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.

Background: eNOS is a calcium/calmodulin dependent enzyme which undergoes several post translational modifications, including acylation with myristate and palmitate, and phosphorylation on numerous residues. As with the other members of the NOS family, eNOS derives the diffusible multifunctional second messenger NO from L arginine through a series of reactions in which L citrulline is an intermediate. eNOS plays an important role in controlling vascular tone, platelet aggregation, and cardiac myocyte function.