Host: Rabbit
Target Protein: SIAH1
IR: Immunogen Range:201-282/282
Clonality: Polyclonal
Isotype: IgG
Entrez Gene: 6477
Swiss Prot: Q8IUQ4
Source: KLH conjugated synthetic peptide derived from human SIAH1:201-282/282
Purification: affinity purified by Protein A
Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background: This gene encodes a protein that is a member of the seven in absentia homolog (SIAH) family. The protein is an E3 ligase and is involved in ubiquitination and proteasome-mediated degradation of specific proteins. The activity of this ubiquitin ligase has been implicated in the development of certain forms of Parkinson's disease, the regulation of the cellular response to hypoxia and induction of apoptosis. Alternative splicing results in several additional transcript variants, some encoding different isoforms and others that have not been fully characterized.
Size: 200ul
Concentration: 1mg/ml
Applications: IHC-P=1:100-500, IHC-F=1:100-500, IF=1:100-500, Flow-Cyt=1ug/Test, ELISA=1:5000-10000
Cross Reactive Species: Rat,Human (predicted: Rabbit,Horse,Cow,Pig,Dog,Chicken,Mouse)
For research use only. Not intended for diagnostic or therapeutic use.