bs-0578R [Primary Antibody]
Rabbit  Anti-Collagen I  Polyclonal Antibody
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Host: Rabbit

Target Protein: Collagen I

IR: Immunogen Range:1321-1400/1464

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 1277

Swiss Prot: P02452

Source: KLH conjugated synthetic peptide derived from human Collagen I C-terminal propeptide:1321-1400/1464 

Purification: affinity purified by Protein A

Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background: This gene encodes the pro-alpha1 chains of type I collagen whose triple helix comprises two alpha1 chains and one alpha2 chain. Type I is a fibril-forming collagen found in most connective tissues and is abundant in bone, cornea, dermis and tendon. Mutations in this gene are associated with osteogenesis imperfecta types I-IV, Ehlers-Danlos syndrome type VIIA, Ehlers-Danlos syndrome Classical type, Caffey Disease and idiopathic osteoporosis. Reciprocal translocations between chromosomes 17 and 22, where this gene and the gene for platelet-derived growth factor beta are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans, resulting from unregulated expression of the growth factor. Two transcripts, resulting from the use of alternate polyadenylation signals, have been identified for this gene. [provided by R. Dalgleish, Feb 2008].

Size: 100ul

Concentration: 1mg/ml

Applications: WB=1:500-2000, IHC-P=1:100-500, IHC-F=1:100-500, IF=1:100-500, ELISA=1:5000-10000

Cross Reactive Species: Human,Mouse,Rat,Dog,Rabbit (predicted: Cow,Horse,Sheep,Monkey)

For research use only. Not intended for diagnostic or therapeutic use.

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