Host: Rabbit
Target Protein: Endostatin
IR: Immunogen Range:
Clonality: Polyclonal
Isotype: IgG
Entrez Gene: 80781
Swiss Prot: P39060
Source: KLH conjugated synthetic peptide derived from human Endostatin:
Purification: affinity purified by Protein A
Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background: This gene encodes the alpha chain of type XVIII collagen. This collagen is one of the multiplexins, extracellular matrix proteins that contain multiple triple-helix domains (collagenous domains) interrupted by non-collagenous domains. The proteolytically produced C-terminal fragment of type XVIII collagen is endostatin, a potent antiangiogenic protein. Mutations in this gene are associated with Knobloch syndrome. The main features of this syndrome involve retinal abnormalities so type XVIII collagen may play an important role in retinal structure and in neural tube closure. Two transcript variants encoding different isoforms have been found for this gene.
Size: 200ul
Concentration: 1mg/ml
Applications: IHC-P=1:100-500
Cross Reactive Species: Rat (predicted: Rabbit,Dog,Mouse,Human)
For research use only. Not intended for diagnostic or therapeutic use.