Host: Mouse
Target Protein: SARS-CoV-2 (2019-nCoV) Nucleocapsid protein, Biotin conjugated
IR: Immunogen Range:full length
Clonality: Monoclonal
Isotype: IgG
Entrez Gene: 43740575
Swiss Prot: P0DTC9
Source: Recombinant SARS-CoV-2 Nucleocapsid Protein:full length
Purification: affinity purified by Protein G
Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background: Coronaviruses are enveloped viruses with a positive-sense RNA genome and with a nucleocapsid of helical symmetry. Coronavirus nucleoproteins localize to the cytoplasm and the nucleolus, a subnuclear structure, in both virus-infected primary cells and in cells transfected with plasmids that express N protein. Coronavirus N protein is required for coronavirus RNA synthesis, and has RNA chaperone activity that may be involved in template switch. Nucleocapsid protein is a most abundant protein of coronavirus. During virion assembly, N protein binds to viral RNA and leads to formation of the helical nucleocapsid. Nucleocapsid protein is a highly immunogenic phosphoprotein also implicated in viral genome replication and in modulating cell signaling pathways. Because of the conservation of N protein sequence and its strong immunogenicity, the N protein of coronavirus is chosen as a diagnostic tool.
Size: 100ul
Concentration: 1mg/ml
Applications:
Cross Reactive Species:
For research use only. Not intended for diagnostic or therapeutic use.