Host: Rabbit
Target Protein: IL-6R alpha
IR: Immunogen Range:20-365/468
Clonality: Polyclonal
Isotype: IgG
Entrez Gene: 3570
Swiss Prot: P08887
Source: Recombinant human IL-6R alpha:20-365/468
Purification: affinity purified by Protein A
Storage: 0.01M PBS(pH7.4) Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background: Interleukin 6 (IL6) is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in immune response. The protein encoded by this gene is a subunit of the receptor complex for IL6. The IL6 receptor is a protein complex consisting of this protein and interleukin 6 signal transducer (IL6ST/GP130/IL6-beta), a receptor subunit also shared by many other cytokines. Dysregulated production of IL6 and this receptor are implicated in the pathogenesis of many diseases, such as multiple myeloma, autoimmune diseases and prostate cancer. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq].
Size: 50ul
Concentration:
Applications: WB=1:500-2000, IHC-P=1:400-800, ELISA=1:5000-10000
Cross Reactive Species: Human
For research use only. Not intended for diagnostic or therapeutic use.