Host: Rabbit

Target Protein: phospho-AMPK alpha-1 (Ser496+Ser502)

IR: Immunogen Range:SG(p-S)IS

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 5562

Swiss Prot: Q13131

Source: KLH conjugated Synthesised phosphopeptide derived from mouse AMPK alpha-1 around the phosphorylation site of Ser496+Ser502:SG(p-S)IS 

Purification: affinity purified by Protein A

Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background: The protein encoded by this gene belongs to the ser/thr protein kinase family. It is the catalytic subunit of the 5'-prime-AMP-activated protein kinase (AMPK). AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq].