Host: Rabbit

Target Protein: KIR2DS4/CD158i

IR: Immunogen Range:221-290/290

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 3809

Swiss Prot: P43632

Source: KLH conjugated synthetic peptide derived from human CD158i:221-290/290 

Purification: affinity purified by Protein A

Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background: The KIR family consists of transmembrane glycoproteins of the Ig superfamily expressed on human NK cells and a subset of human T cells. They are involved in recognition of either MHC class I molecules or unknown ligand on target cells and inhibit cytotoxic activities. KIR2DS4 is an activating receptor of KIR family. KIR2DS4 is a receptor on natural killer (NK) cells for HLA C alleles. It does not inhibit the activity of NK cells.