Host: Rabbit
Target Protein: Growth hormone receptor
IR: Immunogen Range:
Clonality:
Isotype: IgG
Entrez Gene: 2690
Swiss Prot: P10912
Source: KLH conjugated synthetic peptide derived from human Growth hormone receptor:
Purification: affinity purified by Protein A
Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background: This gene encodes a member of the type I cytokine receptor family, which is a transmembrane receptor for growth hormone. Binding of growth hormone to the receptor leads to receptor dimerization and the activation of an intra- and intercellular signal transduction pathway leading to growth. Mutations in this gene have been associated with Laron syndrome, also known as the growth hormone insensitivity syndrome (GHIS), a disorder characterized by short stature. In humans and rabbits, but not rodents, growth hormone binding protein (GHBP) is generated by proteolytic cleavage of the extracellular ligand-binding domain from the mature growth hormone receptor protein. Multiple alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Jun 2011].
Size: 50ul
Concentration: 1mg/ml
Applications: WB=1:500, IHC-P=1:100-500, ICC=1:50-200
Cross Reactive Species: (predicted: Human,Mouse,Rat)
For research use only. Not intended for diagnostic or therapeutic use.