Host: Rabbit
Target Protein: GCLM
IR: Immunogen Range:
Clonality:
Isotype: IgG
Entrez Gene: 2730
Swiss Prot: P48507
Source: Recombinant human GCLM protein:
Purification: affinity purified by Protein A
Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background: Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase, is the first rate limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. Gamma glutamylcysteine synthetase deficiency has been implicated in some forms of hemolytic anemia. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Apr 2015]
Size: 50ul
Concentration: 1mg/ml
Applications: WB=1:500-1000, IHC-P=1:50-100, ICC=1:50, IF=1:50-200, Flow-Cyt=1:50
Cross Reactive Species: Human,Mouse (predicted: Rat)
For research use only. Not intended for diagnostic or therapeutic use.