Host: Rabbit
Target Protein: CD46
IR: Immunogen Range:
Clonality:
Isotype: IgG
Entrez Gene: 4179
Swiss Prot: P15529
Source: KLH conjugated synthetic peptide derived from human CD46:
Purification: affinity purified by Protein A
Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background: CD46 is one of the membrane complement regulatory proteins. CD46 possesses C3b-binding and factor I cofactor activities which play important roles in the regulation of the complement activation pathway. CD46 is widely distributed on blood cells, endothelial cells, epithelial cells and tumor cell lines. CD46 exists as many isoforms in a variety of tissues. The antigen has a broad distribution and is present on leukocytes, platelets, endothelial cells, epithelial cells and fibroblasts. It is strongly expressed on salivary gland ducts and kidney ducts, moderately on lymphocytes and endothelium, and weakly on interstitial tissues and muscle cells, but not on erythrocytes. It is expressed on thymocytes, B cells, monocytes, granulocytes, NK cells, platelets, epithelial and endothelial cells.
Size: 50ul
Concentration: 1mg/ml
Applications: WB=1:1000-5000, IHC-P=1:50-200, IHC-F=1:50-200, ICC=1:50-200
Cross Reactive Species: Human (predicted: Mouse,Rat)
For research use only. Not intended for diagnostic or therapeutic use.