Host: Mouse
Target Protein: SARS-CoV-2 (2019-nCoV) Nucleocapsid
IR: Immunogen Range:full length
Clonality: Monoclonal
Isotype: IgG
Entrez Gene: 43740575
Swiss Prot: P0DTC9
Source: Recombinant SARS-CoV-2 Nucleocapsid Protei:full length
Purification: affinity purified by Protein A
Storage: 1*PBS, 0.03% Proclin300. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:
Coronaviruses are enveloped viruses with a positive-sense RNA genome and with a nucleocapsid of helical symmetry. Coronavirus nucleoproteins localize to the cytoplasm and the nucleolus, a subnuclear structure, in both virus-infected primary cells and in cells transfected with plasmids that express N protein. Coronavirus N protein is required for coronavirus RNA synthesis, and has RNA chaperone activity that may be involved in template switch. Nucleocapsid protein is a most abundant protein of coronavirus. During virion assembly, N protein binds to viral RNA and leads to formation of the helical nucleocapsid. Nucleocapsid protein is a highly immunogenic phosphoprotein also implicated in viral genome replication and in modulating cell signaling pathways. Because of the conservation of N protein sequence and its strong immunogenicity, the N protein of coronavirus is chosen as a diagnostic tool.
This antibodies specific recognition of Sars-Cov-2 (2019-ncov) nucleocapsid. Do not recognize SARS CoV nucleocapsid.
Size: 100ug
Concentration: 1mg/ml
Applications: WB=1:500-2000, ELISA=1:5000-10000
Cross Reactive Species: SARS-CoV-2,SARS-CoV-2
For research use only. Not intended for diagnostic or therapeutic use.