Host: Rabbit
Target Protein: CD163
IR: Immunogen Range:
Clonality:
Isotype: IgG
Entrez Gene: 9332
Swiss Prot: Q86VB7
Source: KLH conjugated synthetic peptide derived from human CD163:
Purification: affinity purified by Protein A
Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background: The protein encoded by this gene is a member of the scavenger receptor cysteine-rich (SRCR) superfamily, and is exclusively expressed in monocytes and macrophages. It functions as an acute phase-regulated receptor involved in the clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages, and may thereby protect tissues from free hemoglobin-mediated oxidative damage. This protein may also function as an innate immune sensor for bacteria and inducer of local inflammation. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2011]
Size: 100ul
Concentration: 1mg/ml
Applications: WB=1:500-1000, IHC-P=1:100-500, IHC-F=1:50-100, Flow-Cyt=1:50
Cross Reactive Species: Human,Mouse,Rat
For research use only. Not intended for diagnostic or therapeutic use.