Host: Rabbit
Target Protein: phospho-ATM (Ser1981)
IR: Immunogen Range:EG(p-S)Q
Clonality:
Isotype: IgG
Entrez Gene: 472
Swiss Prot: Q13315
Source: KLH conjugated Synthesised phosphopeptide derived from human ATM around the phosphorylation site of Ser1981:EG(p-S)Q
Purification: affinity purified by Protein A
Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background: ATM is a 370 kDa nuclear phosphoprotein involved in the autosomal recessive disease Ataxia Telangiectasia (AT). ATM belongs to a novel family of proteins associated with cell cycle regulation, apoptosis, and response to DNA damage repair (DNA damage caused by such things as ionizing irradiation activates ATM kinase). The C terminal region has extensive homology to the catalytic domains of Phosphatidylinositol 3 kinases (PI3 kinases).
Size: 100ul
Concentration: 1mg/ml
Applications: WB=1:300-1000, IHC-P=1:50-100, IHC-F=1:50-100, ICC=1:50-100, IF=1:50-100
Cross Reactive Species: Human (predicted: Mouse)
For research use only. Not intended for diagnostic or therapeutic use.