Host: Mouse

Target Protein: CK18(ready to use)

IR: Immunogen Range:

Clonality: Monoclonal

Isotype: IgG

Entrez Gene: 3875

Swiss Prot: P05783

Source: KLH conjugated synthetic peptide derived from human CK18: 

Purification: affinity purified by Protein A

Storage: 0.01M PBS(pH7.4) with 1% BSA and 0.1% Proclin300 Store at 2-8 °C for one year. Avoid repeated freeze/thaw cycles.

Background: Keratin 18 is a type I cytokeratin. It is, together with its filament partner keratin 8, perhaps the most commonly found products of the intermediate filament gene family. They are expressed in single layer epithelial tissues of the body. Mutations in this gene have been linked to cryptogenic cirrhosis. Two transcript variants encoding the same protein have been found for this gene. Keratin 18 is often used together with keratin 8 and keratin 19 to differentiate cells of epithelial origin from hematopoietic cells in tests that enumerate circulating tumor cells in blood.