Host: Mouse
Target Protein: Oct 4 (1F4)
IR: Immunogen Range:1-100/360
Clonality: Monoclonal
Isotype: IgG
Entrez Gene: 5460
Swiss Prot: Q01860
Source: KLH conjugated synthetic peptide derived from human OCT4:1-100/360
Purification: affinity purified by Protein A
Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background: Expression of the POU-domain transcription factor Octamer-4 (Oct-4) is widely regarded as a hallmark of pluripotent stem cells. The relationship of Oct-4 to pluripotent stem cells is indicated by its tightly restricted expression to undifferentiated pluripotent stem cells. Upon differentiation to somatic lineages, the expression of Oct-4 disappears rapidly. Unlike the majority of pluripotent stem cell markers, the biological role of Oct-4 has been well characterized. Studies performed in mice point to the critical role of Oct-4 in the establishment and/or maintenance of pluripotent stem cells in an uncommitted state.
Size: 50ul
Concentration: 1mg/ml
Applications: WB=1:500-2000, ICC=1:100-200, IF=1:100-200
Cross Reactive Species: (predicted: Human)
For research use only. Not intended for diagnostic or therapeutic use.