Host: Mouse
Target Protein: CK17
IR: Immunogen Range:
Clonality: Monoclonal
Isotype: IgG
Entrez Gene: 3872
Swiss Prot: Q04695
Source: KLH conjugated synthetic peptide derived from human CK17:
Purification: affinity purified by Protein G
Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background: The protein encoded by this gene is a member of the keratin family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. The type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. Unlike its related family members, this smallest known acidic cytokeratin is not paired with a basic cytokeratin in epithelial cells. It is specifically expressed in the periderm, the transiently superficial layer that envelopes the developing epidermis. The type I cytokeratins are clustered in a region of chromosome 17q12-q21. This gene encodes the type I intermediate filament chain keratin 17, expressed in nail bed, hair follicle, sebaceous glands, and other epidermal appendages. Mutations in this gene lead to Jackson-Lawler type pachyonychia congenita and steatocystoma multiplex. [provided by RefSeq, Aug 2008].
Size: 100ul
Concentration: 1mg/ml
Applications: WB=1:500-1000, IHC-P=1:100-500, IHC-F=1:100-500, ICC=1:100, IF=1:20-200
Cross Reactive Species: Human
For research use only. Not intended for diagnostic or therapeutic use.