Host: Rabbit

Target Protein: UCP-2

IR: Immunogen Range:51-120/309

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 7351

Swiss Prot: P55851

Source: KLH conjugated synthetic peptide derived from human UCP-2:51-120/309 

Purification: affinity purified by Protein A

Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background: UCPs facilitate the transfer of anions from the inner to the outer mitochondrial membrane and the return transfer of protons from the outer to the inner mitochondrial membrane. They also reduce the mitochondrial membrane potential in mammalian cells. UCP2 gene is expressed in many tissues, with the greatest expression in skeletal muscle. UCP2 is thought to play a role in non shivering thermogenesis, obesity and diabetes.