Host: Rabbit

Target Protein: GPR49/LGR5

IR: Immunogen Range:211-310/907

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 8549

Swiss Prot: O75473

Source: KLH conjugated synthetic peptide derived from human GPR49/LGR5:211-310/907 

Purification: affinity purified by Protein A

Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background: The protein encoded by this gene is a leucine-rich repeat-containing receptor (LGR) and member of the G protein-coupled, 7-transmembrane receptor (GPCR) superfamily. The encoded protein is a receptor for R-spondins and is involved in the canonical Wnt signaling pathway. This protein plays a role in the formation and maintenance of adult intestinal stem cells during postembryonic development. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2015]